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Latest from Modernising Medical Microbiology

MMM crowdsourcing the fight against TB

An online project has been launched by MMM researchers to study antibiotic resistance in Tuberculosis (TB) with the help of the public.

You can try out the project for yourself on the Zooniverse website which contains instructions for how to take part, and help us change the way TB is diagnosed and treated.

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MMM’s work helps elucidate that antibiotics played the main role in driving mid-2000s C. difficile epidemics

MMM researchers at Oxford and Leeds, and PHE, have published a major piece of research proving that overuse of antibiotics was the main driver of the C. difficile (C. diff) epidemic that took place in the UK by mid-2000s.  In a nutshell, the study published online on 24/1/17 in The Lancet Infectious Diseases, showed that within a group of measures to control the outbreak, restrictions on fluoroquinolone use had the highest impact.

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Staphylococcus aureus

Staphylococcus aureus (or Staph. aureus) is a bacterium that lives harmlessly on the skin. However, Staph. aureus can also cause infections, particularly in hospitalised patients. Hospital staff work hard to prevent patients from developing Staph aureus infections. They do this in a number of ways including regularly washing their hands, wearing protective clothing (gloves and aprons) and cleaning the hospital environment. Despite these measures patients continue to pick up Staph. aureus infection in hospital.

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About Modernising Medical Microbiology

Modernising Medical Microbiology is a research group aiming to transform how we analyse and treat infections, to improve patient care.

We aim to:

1) Modernise the way we analyse infections, bringing cutting-edge scientific techniques to clinical care.

2) Transform they way we study the treatment of patients with infections, using large databases of hospital electronic information, to identify trends in how infections are behaving, and ways patient care can be improved.

3) Use techniques such as DNA analysis of bacteria and viruses to better understand how infections spread, how to treat them, and how to prevent them in the future.

4) Study how bacteria become resistant to antibiotics, and more difficult to treat, and how to prevent this.

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Modernising Medical Microbiology studies a number of infections, in particular Staphylococcus aureus (including MRSA), Clostridium difficile (C. diff), Mycobacterium tuberculosis (TB),  and the Enterobacteriaceae family (Escherichia coli, Klebsiella species and others).  You can learn more about these bacteria here