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Latest from Modernising Medical Microbiology

MMM’s work helps elucidate that antibiotics played the main role in driving mid-2000s C. difficile epidemics

MMM researchers at Oxford and Leeds, and PHE, have published a major piece of research proving that overuse of antibiotics was the main driver of the C. difficile (C. diff) epidemic that took place in the UK by mid-2000s.  In a nutshell, the study published online on 24/1/17 in The Lancet Infectious Diseases, showed that within a group of measures to control the outbreak, restrictions on fluoroquinolone use had the highest impact.

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Safely reducing antibiotic use in hospitals

In research published today in the BMJOpen, Modernising Medical Microbiology researchers have shown that it may be possible to use up to 30% less antibiotics in acutely ill patients without adverse consequences. However fewer antibiotics may mean more patients end up being admitted overnight.

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Whole-genome sequencing to combat spread of Gonorrhoea

Doctors and scientists from MMM, Public Health England and The Royal Sussex County Hospital, Brighton published their whole-genome sequencing based tool to track the spread of Neisseria gonorrhoea infections in The Lancet Infectious Diseases today.

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About Modernising Medical Microbiology

Modernising Medical Microbiology is a research group aiming to transform how we analyse and treat infections, to improve patient care.

We aim to:

1) Modernise the way we analyse infections, bringing cutting-edge scientific techniques to clinical care.

2) Transform they way we study the treatment of patients with infections, using large databases of hospital electronic information, to identify trends in how infections are behaving, and ways patient care can be improved.

3) Use techniques such as DNA analysis of bacteria and viruses to better understand how infections spread, how to treat them, and how to prevent them in the future.

4) Study how bacteria become resistant to antibiotics, and more difficult to treat, and how to prevent this.

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Modernising Medical Microbiology studies a number of infections, in particular Staphylococcus aureus (including MRSA), Clostridium difficile (C. diff), Mycobacterium tuberculosis (TB),  and the Enterobacteriaceae family (Escherichia coli, Klebsiella species and others).  You can learn more about these bacteria here